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May 07, 2020

April 2020: Dan is co-organizing a workshop on left-right patterning

May 07, 2020/ Daniel Grimes
April 2020: Dan is co-organizing a workshop on left-right patterning

There are funded places for ECRs available. Find out more an apply here.

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May 07, 2020/ Daniel Grimes/
March 29, 2020

March 2020: Dan becomes an Associate Member of the Knight Campus

March 29, 2020/ Daniel Grimes
March 2020: Dan becomes an Associate Member of the Knight Campus

We look forward to interacting more closely with the Knight Campus’ faculty and initiatives.

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March 29, 2020/ Daniel Grimes/
March 21, 2020

March 2020: Grad student Katie Fisher joins the lab

March 21, 2020/ Daniel Grimes
March 2020: Grad student Katie Fisher joins the lab

Welcome Katie! She will work on how embryonic symmetry is broken.

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March 21, 2020/ Daniel Grimes/
March 17, 2020

March 2020: The lab closes its doors

March 17, 2020/ Daniel Grimes
March 2020: The lab closes its doors

To help slow the spread of COVID-19, the lab is suspending all wet work. Our members will be staying at home. We will be keeping in regular contact with Zoom and we’ll work (paper and grant writing, data analysis) if we can.

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March 17, 2020/ Daniel Grimes/
March 17, 2020

March 2020: Zoe and Gabriel both pass their qualifying exams!

March 17, 2020/ Daniel Grimes
March 2020: Zoe and Gabriel both pass their qualifying exams!

Congratulations

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March 17, 2020/ Daniel Grimes/
February 20, 2020

Feb 2020: The lab receives a grant from the Medical Research Foundation

February 20, 2020/ Daniel Grimes
Feb 2020: The lab receives a grant from the Medical Research Foundation

We are grateful for their support of our work on left-right patterning

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February 20, 2020/ Daniel Grimes/
February 03, 2020

Jan 2020: Two new rotation students join the lab

February 03, 2020/ Daniel Grimes
Jan 2020: Two new rotation students join the lab

Welcome Hannah Markovic and Katie Fisher (in pic, with Buster)!

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February 03, 2020/ Daniel Grimes/
December 02, 2019

Nov 2019: Article published about heart asymmetry

December 02, 2019/ Daniel Grimes
Nov 2019: Article published about heart asymmetry

Congrats especially to Gabriel and Zoe for their first ever publication!

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December 02, 2019/ Daniel Grimes/
November 19, 2019

Nov 2019: Colin wins presentation award at ABRCMS

November 19, 2019/ Daniel Grimes
Nov 2019: Colin wins presentation award at ABRCMS

Congratulations Colin!

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November 19, 2019/ Daniel Grimes/
November 18, 2019

Nov 2019: Cynthia and Colin present at ABRCMS

November 18, 2019/ Daniel Grimes
Nov 2019: Cynthia and Colin present at ABRCMS

They did an amazing job presenting their SPUR-funded summer projects. Well done!

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November 18, 2019/ Daniel Grimes/
October 25, 2019

Oct 2019: Sam Craig joins the lab

October 25, 2019/ Daniel Grimes
Oct 2019: Sam Craig joins the lab

He will work alongside Zoe on cilia and body patterning. Welcome Sam!

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October 25, 2019/ Daniel Grimes/
September 28, 2019

Sept 2019: Funding award from NIAMS

September 28, 2019/ Daniel Grimes
Sept 2019: Funding award from NIAMS

The lab is awarded R00 funding from NIAMS.

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September 28, 2019/ Daniel Grimes/
September 06, 2019

Sept 2019: Article published in Nature Communications

September 06, 2019/ Daniel Grimes
Sept 2019: Article published in Nature Communications

About Polycystin-2, cilia, and kidney cysts

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September 06, 2019/ Daniel Grimes/
August 16, 2019

August 2019: Review article published in Development

August 16, 2019/ Daniel Grimes
August 2019: Review article published in Development

Discusses the generation and maintenance of symmetries in the vertebrate body.

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August 16, 2019/ Daniel Grimes/
August 07, 2019

August 2019: Beth and Dan attend FASEB Cilia 2019

August 07, 2019/ Daniel Grimes
August 2019: Beth and Dan attend FASEB Cilia 2019

…in beautiful Snowmass, CO

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August 07, 2019/ Daniel Grimes/
August 07, 2019

August 2019: Preprint from Murphy lab released

August 07, 2019/ Daniel Grimes
August 2019: Preprint from Murphy lab released

Demonstrates that control of folate metabolism is critical for aging axon regeneration in C. elegans and zebrafish.

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August 07, 2019/ Daniel Grimes/
July 21, 2019

July 2019: Dan presents at ZDM12 conference in Boston

July 21, 2019/ Daniel Grimes
July 2019: Dan presents at ZDM12 conference in Boston

He discusses recent CRISPR screens to understand left-right patterning

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July 21, 2019/ Daniel Grimes/
July 03, 2019

July 2019: New postdoc Beth Bearce joins the lab

July 03, 2019/ Daniel Grimes
July 2019: New postdoc Beth Bearce joins the lab

She is joining us from the Lowery Lab at Boston College

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July 03, 2019/ Daniel Grimes/
July 03, 2019

June 2019: SPUR student Cynthia Sabazali joins the lab

July 03, 2019/ Daniel Grimes
June 2019: SPUR student Cynthia Sabazali joins the lab

She joins us for the summer from UC Merced

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July 03, 2019/ Daniel Grimes/
June 21, 2019

June 2019: the lab is awarded a gift from the Donald E. and Delia B. Baxter Foundation

June 21, 2019/ Daniel Grimes
June 2019: the lab is awarded a gift from the Donald E. and Delia B. Baxter Foundation

We are grateful for their support of our work on spinal symmetry and scoliosis

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June 21, 2019/ Daniel Grimes/
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Grimes lab

Many features of vertebrate bodies, such as the skeleton and the limbs, display symmetry between left and right. By contrast, the internal organs exhibit left-right asymmetries in their position and structure.


In the Grimes lab, we use genetic, genomic, and imaging procedures to understand the basis of these symmetries and asymmetries during development and growth. We are also interested in how they contribute to human diseases such as birth defects and scoliosis.


For our work, we primarily use the zebrafish model organism.

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